Publications

2020

Sex-specific effects of mitochondrial haplotype on metabolic rate in Drosophila melanogaster support predictions of the Mother’s Curse hypothesis. Venkatesh Nagarajan-Radha, Ian Aitkenhead, David J Clancy, Steven L Chown, Damian K Dowling. Philosophical Transactions of the Royal Society B. Published January 2020. Link

A new member in the Argonaute crew: the mt-miRNAs. Andrea Pozzi, Damian Kimon Dowling. bioRxiv. Published January 2020. Link

2019

Controlling for body size leads to inferential biases in the biological sciences. Björn Rogell, Damian K Dowling, Arild Husby. Evolution Letters. Published December 2019. Link

Field-realistic antidepressant exposure disrupts group foraging dynamics in mosquitofish. Jake M Martin, Minna Saaristo, Hung Tan, Michael G Bertram, Venkatesh Nagarajan-Radha, Damian K Dowling, Bob BM Wong. Biology letters. Published November 2019. Link

Mother’s curse and indirect genetic effects: do males matter to mitochondrial genome evolution? Thomas A Keaney, Heidi WS Wong, Damian K Dowling, Therésa M Jones, Luke Holman. Journal of Evolutionary Biology. Published October 2019. Link

The cuticle inward barrier in Drosophila melanogaster is shaped by mitochondrial and nuclear genotypes and a sex-specific effect of diet. Wei Dong, Ralph Dobler, Damian K Dowling, Bernard Moussian. PeerJ Inc. Published October 2019. Link

Beyond the powerhouse: integrating mitonuclear evolution, physiology, and theory in comparative biology. Justin C Havird, Ryan J Weaver, Liliana Milani, Fabrizio Ghiselli, Ryan Greenway, Adam J Ramsey, Ana G Jimenez, Damian K Dowling, Wendy R Hood, Kristi L Montooth, Suzanne Estes, Patricia M Schulte, Inna M Sokolova, Geoffrey E Hill.
Integrative and comparative biology. Published October 2019. Link

Challenges and Prospects for Testing the Mother’s Curse Hypothesis. DK Dowling, RE Adrian. Integrative and Comparative Biology. Published June 2019. Link

Transgenerational obesity and healthy ageing in Drosophila. TLC Carter, DK Dowling, R Robker, MDW Piper. The Journals of Gerontology: Series A. Published June 2019. Link

The genomic origins of small mitochondrial RNAs: are they transcribed by the mitochondrial DNA or by mitochondrial pseudogenes within the nucleus (NUMTs)? A Pozzi, DK Dowling. Genome Biology and Evolution. Published June 2019. Link

Selfish mitonuclear conflict. JC Havird, ES Forsythe, AM Williams, JH Werren, DK Dowling, DB Sloan. Current Biology 29 (11), R496-R511. Published June 2019. Link

Assessing the fitness consequences of mitonuclear interactions in natural populations. GE Hill, JC Havird, DB Sloan, RS Burton, C Greening, DK Dowling. Biological Reviews 94 (3), 1089-1104. Published June 2019. Link 75

Interactions between mitochondrial haplotype and dietary macronutrient ratios confer sex-specific effects on longevity in Drosophila melanogaster. V Nagarajan-Radha, J Rapkin, J Hunt, DK Dowling. The Journals of Gerontology: Series A. Published May 2019. Link

Reply: Mitochondrial replacement and its effects on human health: accounting for non-independence of data in meta-analyses. R Dobler, DK Dowling, EH Morrow, K Reinhardt. Human reproduction update. Published March 2019. Link

Public attitudes towards novel reproductive technologies: a citizens’ jury on mitochondrial donation. AJ Newson, S de Lacey, DK Dowling, S Murray, CM Sue, DR Thorburn, L Gillam, C Degeling. Human Reproduction. Published March 2019. Link

2018

Masculinization of gene expression is associated with male quality in Drosophila melanogaster. R Dean, C Hammer, V Higham, DK Dowling. Evolution 72 (12), 2736-2748. Published December 2018. Link

Maternal age effects on fecundity and offspring egg‐to‐adult viability are not affected by mitochondrial haplotype. RE Koch, JM Phillips, MF Camus, DK Dowling. Ecology and evolution 8 (22), 10722-10732. Published November 2018. Link

The Cytoplasm Affects the Epigenome in Drosophila melanogaster. C Grunau, S Voigt, R Dobler, D Dowling, K Reinhardt. Epigenomes 2 (3), 17. Published September 2018. Link

The effects of a bacterial challenge on reproductive success of fruit flies evolved under low or high sexual selection. M Nystrand, EJ Cassidy, DK Dowling. Ecology and evolution 8 (18), 9341-9352. Published September 2018. Link

Experimental evidence that thermal selection shapes mitochondrial genome evolution. Z Lajbner, R Pnini, MF Camus, J Miller, DK Dowling. Scientific reports 8 (1), 9500. Published June 2018. Link

Mitochondrial genetic effects on reproductive success: signatures of positive intrasexual, but negative intersexual pleiotropy. MF Camus, DK Dowling. Proceedings of The Royal Society B-Biological Sciences 285 (1879), 20180187. Published May 2018. Link

Transgenerational effects of maternal sexual interactions in seed beetles. Susanne RK Zajitschek, Damian K Dowling, Megan L Head, Eduardo Rodriguez-Exposito, Francisco Garcia-Gonzalez. Heredity 121, 282-291. Published May 2018. Link

A systematic review and meta-analysis reveals pervasive effects of germline mitochondrial replacement on components of health. R Dobler, DK Dowling, EH Morrow, K Reinhardt. Human reproduction update 24 (5), 519-534. Published May 2018. Link

Maternal inheritance of mitochondria: implications for male fertility? RC Vaught, DK Dowling. Reproduction 155 (4), R159-R168. Published April 2018. Link

Coadaptation of mitochondrial and nuclear genes, and the cost of mother’s curse. T Connallon, MF Camus, EH Morrow, DK Dowling. Proceedings of The Royal Society B-Biological Sciences 285 (1871), 20172257. Published January 2018. Link

2017

Mitochondrial genetic effects on reproductive success: signatures of positive intrasexual, but negative intersexual pleiotropy. MF Camus, DK Dowling. Proceedings of The Royal Society B-Biological Sciences 285 (1879), 20180187. Published January 2017. Link

Experimental evidence that thermal selection shapes mitochondrial genome evolution. Z Lajbner, R Pnini, MF Camus, J Miller, DK Dowling. Scientific reports 8 (1), 9500. Published January 2017. Link

mtDNA polymorphism and metabolic inhibition affect sperm performance in conplastic mice. Maximiliano Tourmente, Misa Hirose, Saleh Ibrahim, Damian K Dowling, Daniel M Tompkins, Eduardo RS Roldan, Neil J Gemmell. Reproduction 154 (4), 341-354. Published October 2017. Link

Experimental support that natural selection has shaped the latitudinal distribution of mitochondrial haplotypes in Australian Drosophila melanogaster. MF Camus, JN Wolff, CM Sgrò, DK Dowling. Molecular Biology and Evolution 34 (10), 2600-2612. Published June 2017. Link

Introduction of a male-harming mitochondrial haplotype via ‘Trojan Females’ achieves population suppression in fruit flies. JN Wolff, NJ Gemmell, DM Tompkins, DK Dowling. eLife 6, e23551. Published March 2017. Link

No effect of mitochondrial genotype on reproductive plasticity following exposure to a non-infectious pathogen challenge in female or male Drosophila. M Nystrand, EJ Cassidy, DK Dowling. Scientific reports 7, 42009. Published February 2017. Link

Mitochondrial genome variation affects the mutation rate of the nuclear genome in Drosophila melanogaster. JN Wolff, MF Camus, DK Dowling, B Rogell. BioRXiV, 122234. Published January 2017. Link

2016

Reproductive activity triggers accelerated male mortality and decreases lifespan: genetic and gene expression determinants in Drosophila. AT Branco, L Schilling, K Silkaitis, DK Dowling, B Lemos. Heredity 118 (3), 221. Published October 2016. Link

Evolutionary implications of mitochondrial genetic variation: mitochondrial genetic effects on OXPHOS respiration and mitochondrial quantity change with age and sex in fruit flies. JN Wolff, N Pichaud, MF Camus, G Côté, PU Blier, DK Dowling. Journal of Evolutionary Biology 29 (4), 736-747. Published January 2016. Link

Mitonuclear interactions, mtDNA-mediated thermal plasticity, and implications for the Trojan Female Technique for pest control. JN Wolff, DM Tompkins, NJ Gemmell, DK Dowling. Scientific Reports 6, 30016. Published January 2016. Link

Transgenerational plasticity following a dual pathogen and stress challenge in fruit flies. M Nystrand, EJ Cassidy, DK Dowling. BMC Evolutionary Biology 16 (1), 171. Published August 2016. Link

2015

Complete mitochondrial genome sequences of thirteen globally sourced strains of fruit fly (Drosophila melanogaster) form a powerful model for mitochondrial research. JN Wolff, MF Camus, DJ Clancy, DK Dowling. Mitochondrial DNA Part A 27 (6), 4672-4674. Published December 2015. Link

Intergenomic interactions between mitochondrial and Y‐linked genes shape male mating patterns and fertility in Drosophila melanogaster. WKW Yee, B Rogell, B Lemos, DK Dowling. Evolution 69 (11), 2876-2890. Published September 2015. Link

Single nucleotides in the mtDNA sequence modify mitochondrial molecular function and are associated with sex-specific effects on fertility and aging. MF Camus, JBW Wolf, EH Morrow, DK Dowling. Current Biology 25 (20), 2717-2722. Published October 2015. Link

The Trojan Female Technique for pest control: a candidate mitochondrial mutation confers low male fertility across diverse nuclear backgrounds in Drosophila melanogaster. DK Dowling, DM Tompkins, NJ Gemmell. Evolutionary applications 8 (9), 871-880. Published October 2015. Link

The evolution of sex: a new hypothesis based on mitochondrial mutational erosion. JC Havird, MD Hall, DK Dowling. Bioessays 37 (9), 951-958. Published July 2015. Link

Context‐dependent effects of Y chromosome and mitochondrial haplotype on male locomotive activity in Drosophila melanogaster. R Dean, B Lemos, DK Dowling. Journal of Evolutionary Biology. Published August 2015. Link

Risks inherent to mitochondrial replacement. EH Morrow, K Reinhardt, JN Wolff, DK Dowling. EMBO Reports 16 (5), 541-544. Published May 2015. Link

Transgenerational effects of sexual interactions and sexual conflict: non-sires boost the fecundity of females in the following generation. F Garcia-Gonzalez, DK Dowling. Biology Letters 11 (3), 20150067. Published March 2015. Link

2014

Transgenerational interactions involving parental age and immune status affect female reproductive success in Drosophila melanogaster. M Nystrand, DK Dowling. Proceedings of the Royal Society B: Biological Sciences 281 (1794), 20141242. Published October 2014. Link

Aging: manipulating sex differences. DK Dowling. Current Biology 24 (20), R996-R998. Published October 2014. Link

A meta‐analysis of the strength and nature of cytoplasmic genetic effects. R Dobler, B Rogell, F Budar, DK Dowling. Journal of Evolutionary Biology. Published September 2014. Link

The costs of being male: are there sex-specific effects of uniparental mitochondrial inheritance? M Beekman, DK Dowling, DK Aanen. Philosophical Transactions of the Royal Society B: Biological Sciences 369. Published May 2014. Link

Mitonuclear interactions: evolutionary consequences over multiple biological scales. JN Wolff, ED Ladoukakis, JA Enríquez, DK Dowling. Philosophical Transactions of the Royal Society B: Biological Sciences 369. Published May 2014. Link

Mito-nuclear interactions as drivers of gene movement on and off the X-chromosome. B Lemos, DK Dowling. BMC Genomics 15 (1), 330. Published May 2014. Link

Dose‐dependent effects of an immune challenge at both ultimate and proximate levels in Drosophila melanogaster. M Nystrand, DK Dowling. Journal of Evolutionary Biology 27 (5), 876-888. Published April 2014. Link

Evolutionary perspectives on the links between mitochondrial genotype and disease phenotype. DK Dowling. Biochimica et Biophysica Acta (BBA)-General Subjects 1840, 1393-1403. Published April 2014. Link

Maternal sexual interactions affect offspring survival and ageing. DK Dowling, BR Williams, F Garcia‐Gonzalez. Journal of Evolutionary Biology 27 (1), 88-97. Published January 2014. Link

2013

Context-dependent expression of sperm quality in the fruitfly. DP Decanini, BBM Wong, DK Dowling. Biology letters 9 (6), 20130736. Published December 2013. Link

Mitochondrial replacement, evolution, and the clinic. K Reinhardt, DK Dowling, EH Morrow. Science 341 (6152), 1345-1346. Published September 2013. Link

In vivo male fertility is affected by naturally occurring mitochondrial haplotypes. WKW Yee, KL Sutton, DK Dowling. Current Biology 23 (2), R55-R56. Published January 2013. Link

2012

Aging: evolution of life span revisited. DK Dowling. Current Biology 22 (22), R947-R949. Published November 2012. Link

Mitochondria, maternal inheritance, and male aging. MF Camus, DJ Clancy, DK Dowling. Current Biology 22 (18), 1717-1721. Published September 2012. Link

A multivariate test of evolutionary constraints for thermal tolerance in Drosophila melanogaster. BR Williams, B Van Heerwaarden, DK Dowling, CM Sgrò. Journal of Evolutionary Biology 25 (7), 1415-1426. Published May 2012. Link

Ejaculate economics: testing the effects of male sexual history on the trade-off between sperm and immune function in Australian crickets. DK Dowling, LW Simmons. PloS One 7 (1), e30172. Published January 2012. Link

2011

Effects of vitamin E and beta‐carotene on sperm competitiveness. M Almbro, DK Dowling, LW Simmons. Ecology letters 14 (9), 891-895. Published July 2011. Link

Complex Genotype by Environment interactions and changing genetic architectures across thermal environments in the Australian field cricket, Teleogryllus oceanicus. M Nystrand, DK Dowling, LW Simmons. BMC Evolutionary Biology 11 (1), 222. Published July 2011. Link

Experimental evidence supports a sex-specific selective sieve in mitochondrial genome evolution. P Innocenti, EH Morrow, DK Dowling. Science 332 (6031), 845-848. Published May 2011. Link

2010

Genetic architecture of metabolic rate: environment specific epistasis between mitochondrial and nuclear genes in an insect. G Arnqvist, DK Dowling, P Eady, L Gay, T Tregenza, M Tuda, DJ Hosken. Evolution: International Journal of Organic Evolution 64 (12), 3354-3363. Published November 2010. Link

Cytonuclear interactions and the economics of mating in seed beetles. DK Dowling, T Meerupati, G Arnqvist. The American Naturalist 176 (2), 131-140. Published June 2010. Link

Maternal effects, but no good or compatible genes for sperm competitiveness in Australian crickets. DK Dowling, M Nystrand, LW Simmons. Evolution: International Journal of Organic Evolution 64 (5), 1257-1266. Published May 2010. Link

2009

Applying the genetic theories of ageing to the cytoplasm: cytoplasmic genetic covariation for fitness and lifespan. DK Dowling, AA Maklakov, U Friberg, F Hailer. Journal of Evolutionary Biology 22 (4), 818-827. Published April 2009. Link

Reactive oxygen species as universal constraints in life-history evolution. DK Dowling, LW Simmons. Proceedings of the Royal Society B: Biological Sciences 276 (1663), 1737-1745. Published May 2009. Link

2008

Evolutionary implications of non-neutral mitochondrial genetic variation. DK Dowling, U Friberg, J Lindell. Trends in ecology & evolution 23 (10), 546-554. Published October 2008. Link

No evidence of mitochondrial genetic variation for sperm competition within a population of Drosophila melanogaster. U Friberg, DK Dowling. Journal of Evolutionary Biology 21 (6), 1798-1807. Published November 2008. Link

2007

Effects of cytoplasmic genes on sperm viability and sperm morphology in a seed beetle: implications for sperm competition theory? DK Dowling, AL Nowostawski, G Arnqvist. Journal of Evolutionary Biology 20 (1), 358-368. Published January 2007. Link

Temperature‐specific outcomes of cytoplasmic‐nuclear interactions on egg‐to‐adult development time in seed beetles. DK Dowling, KC Abiega, G Arnqvist. Evolution 61 (1), 194-201. Published January 2007. Link

Intergenomic epistasis for fitness: within-population interactions between cytoplasmic and nuclear genes in Drosophila melanogaster. DK Dowling, U Friberg, F Hailer, G Arnqvist. Genetics 175 (1), 235-244. Published January 2007. Link

A comparison of nuclear and cytoplasmic genetic effects on sperm competitiveness and female remating in a seed beetle. DK Dowling, U Friberg, G Arnqvist. Journal of Evolutionary Biology 20 (6), 2113-2125. Published November 2007. Link

2006

Combined influence of maternal and paternal quality on sex allocation in red‐capped robins. DK Dowling, RA Mulder. Journal of Evolutionary Biology 19 (2), 440-449. Published March 2006. Link

Red plumage and its association with reproductive success in red-capped robins. DK Dowling, RA Mulder. Annales Zoologici Fennici, 311-321. Published August 2006. Link

Within‐population variation in cytoplasmic genes affects female life span and aging in Drosophila melanogaster. AA Maklakov, U Friberg, DK Dowling, G Arnqvist. Evolution 60 (10), 2081-2086. Published October 2006. Link

Pre-2005

The evolution of egg rejection by cuckoo hosts in Australia and Europe. NE Langmore, RM Kilner, SHM Butchart, G Maurer, NB Davies, A Cockburn, NA Macgregor, A Peters, MJL Magrath, DK Dowling. Behavioral Ecology 16 (4), 686-692. Published April 2005. Link

Breeding ecology of the red-capped robin. DK Dowling. Australian Journal of Zoology. Published February 2004. Link

Breeding biology of the red-capped robin. DK Dowling. Australian Journal of Zoology 51 (6), 533-549. Published February 2004. Link

Novel polymorphic microsatellite markers for paternity analysis in the red‐capped robin (Petroica goodenovii: Aves). DK Dowling, GJ Adcock, RA Mulder. Molecular Ecology Notes 3 (4), 517-519. Published August 2003. Link

Dispersal and recruitment of juvenile Red-capped Robins, Petroica goodenovii. DK Dowling, M Antos, T Sahlman. Emu-Austral Ornithology 103 (3), 199-205. Published October 2003. Link

No effects of a feather mite on life-history components and grooming behaviour in the Seychelles warbler, Acrocephalus sechellensis. DK Dowling, DS Richardson, J Komdeur Behavioral. Ecology and Sociobiology 50, 257-262. Published August 2001. Link

Feather mite loads influenced by salt exposure, age and reproductive stage in the Seychelles warbler Acrocephalus sechellensis. DK Dowling, DS Richardson, K Blaakmeer, J Komdeur. Journal of Avian Biology 32 (4), 364-369. Published December 2001. Link